Intelligent Antibody Discovery

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Engineered cell surface expression of membrane immunoglobulin as a means to identify monoclonal antibody-secreting hybridomas

Posted on July 15th, 2015

Research paper on monoclonal antibodies (mAbs) published in Journal of Immunological Methods describing a novel system in which mAb-secreting hybridoma cells were induced to co-express significant amounts of the membrane form of the secreted immunoglobulin (Ig) on their surfaces and are efficiently recovered by fluorescent activated cell sorting (FACS).