Intelligent Antibody Discovery

AbeoMouse™

AbeoMouse – Expression of Antibody on Surface of Affinity Matured B-Cell

Triple transgenic mouse engineered with enhanced immune response and with ability for its affinity matured B-cells (Plasmacytes) to display on their surface the antibody each secretes

  • Rapid identification of antigen specific plasmacytes from the complete highly diverse natural B-cell repertoire
  • Direct selection of plasmacytes secreting antibodies with other desired functions